MRI在诊断神经变性和痴呆中的价值：脑萎缩视觉评分量表模式 ...

CLINICAL RELEVANCE STATEMENT

Brain imaging is recommended in all current diagnostic dementia guidelines. Recently they also recommend the application of atrophy rating scales to assess structural changes in the brain of elderlypatients, such as the medial temporal lobe atrophy by Scheltens.

However, there is still low uptake in routine clinical setting and knowledge of the neuroimagingstrategies available and MRI rating scales is needed in order to encourage clinicians and radiologists to use them.

临床相关声明

当前，所有诊断性痴呆指南均建议施行脑影像检查。 最近指南还建议使用萎缩等级量表来评估老年患者大脑的结构变化，例如Scheltens的内侧颞叶萎缩。

然而，在常规临床工作中对神经影像学知识的掌握仍然不足，需要鼓励临床医生和放射科医生使用MRI评分量表。

The purpose of this exhibit is: 

1. To review the neuroimaging findings in normal brain aging 

2. To explain the utility of MRI in the evaluation of cognitive impairment or dementia, and particularly the role of different proposed and established rating scales for specific brain regions 

3. To emphasize the importance of structured reporting in a dementia clinical setting

本讲座的目的是：

1.回顾正常脑老化中的神经影像学表现

2.阐述MRI在评估认知障碍或痴呆症中的价值，尤其是对特定脑区提出和建立的不同等级量表的作用

3.强调结构化报告在痴呆症临床诊断工作中的重要性

Normal aging is a cause or a precursor to neurodegenerative diseases?

To what extent these aging alterations affect brain function?

Is pathological degeneration an expression of accelerated aging?

正常衰老是神经退行性疾病的原因还是先兆？

这些衰老变化在多大程度上影响大脑功能？

病理性变性是加速衰老的一种表现吗？

Mean score for cortical atrophy throughout the completecerebrum:

• 0: no cortical atrophy

• 1: mild atrophy: opening of sulci

• 2: moderate atrophy: volume loss of gyri

• 3: severe (end-stage) atrophy: 'knife blade' atrophy.

整个大脑皮层萎缩的平均评分：

•0：无皮质萎缩

•1：轻度萎缩：脑沟增宽

•2：中度萎缩：脑回体积减少

•3：严重（末期）萎缩：“刀刃”萎缩。