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Meta分析十点写作精要模板(前五点)

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发表于 2022-4-29 14:46:42 | 显示全部楼层 |阅读模式
本帖最后由 kexue 于 2022-4-29 14:48 编辑

第一点:研究目的的撰写
ObjectivesThe aim of this systematic review was to determine the risks and benefits of early (< 48 h) compared to late (≥ 48 h) initiation of pharmacologic VTEp in adult trauma patients with blunt abdominal solid organ injury managed nonoperatively. The primary objective was to determine whether early initiation of pharmacologic VTEp is associated with a difference in the rate of failure of NOM, compared to late initiation. Secondary objectives were to evaluate differences in risk of DVT and pulmonary embolism (PE), blood transfusion, mortality, and other bleeding complications.
这个研究目的写的非常好,首先是用一个“aim”引出研究的总体目标,并且使用一句话进行了概括。然后分层次通过“The primary objective  ”和 “Secondary objectives ”引出研究的两个目的,非常的清晰明了。
第二点:研究报告规范和注册
The Cochrane Handbook for Systematic Reviews of Interventions and The Preferred Reporting Items for Systematic Review and Meta-Analysis (PRISMA) checklist guided protocol development and reporting . The protocol was registered with PROSPERO (CRD42021241143).
这个句话提供给我们一个非常好的写作模板。通过两句话概括了meta分析的报告规范和注册信息,非常值得我们参考和套用。

第三点:研究选择和数据的提取
Titles, abstracts, and potentially eligible full texts were reviewed independently and in duplicate. Eligibility criteria for full-text screening were applied using an electronic eligibility checklist (Additional file 2: Appendix B). Data collection was performed independently and in duplicate. All discrepancies were resolved by consensus or a third author
这个模板清楚的交代了研究的选择过程和数据的提取过程,并告知了当遇到矛盾时候如何解决,不拖泥带水,字字有用,没有多余的单词。

第四点:研究结果的撰写
OutcomesPrimary outcomeThe primary outcome was the proportion of patients in each study arm who failed NOM and required either surgical or radiological intervention for hemostasis after initiation of pharmacologic VTEp. Patients who were initially treated with angioembolization prior to VTEp initiation were not considered to have failed NOM (Additional file 3, Additional file 4).Secondary outcomesSecondary outcomes included need for packed red blood cell (pRBC) transfusion and the number of units of pRBCs transfused following initiation of VTEp, risk of VTE (DVT and PE), mortality, and other bleeding complications (e.g., intracranial hemorrhage).这个模板就不用过多的介绍了,之前我们已经多次给大家强调过了,研究结果的撰写方法,一定分出来主要研究结果指标和次要研究结果指标。这篇研究提供非常好的写作模板。

第五点:研究质量
Risk of bias in individual studiesRisk of bias for each included study was assessed in duplicate by independent reviewers using the Risk of Bias in Non-Randomized Studies of Interventions (ROBINS-I) tool .这是研究质量评估工具的撰写模板。其实我们在方法学部分,真的不一定要非常详细的描述文献质量评估工具,仅仅就可以像这篇范文一样,简单交代一下使用的工具就可以,然后上一篇参考文献就可以了。原文:https://wjes.biomedcentral.com/articles/10.1186/s13017-022-00423-1
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