血清肿瘤的过去、现在和未来（液体活检） 肺癌标志物

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血清肿瘤的过去、现在和未来（液体活检）肺癌标志物：放射科医师入门.
The Past, Present, and Future (Liquid Biopsy) of Serum Tumor Markers in Lung Cancer: A Primer for the Radiologist.

肺癌仍然是全世界的主要死亡原因。 在早期准确诊断肺癌并监测对治疗的反应的能力对于降低与该疾病相关的发病率和死亡率至关重要。 血清肿瘤标志物已被确定为可能有助于肺癌诊断和监测的潜在生物标志物。 这些标志物与横断面成像相结合，可能会产生更强大的筛查和监测方案。 血清肿瘤标志物在肺癌中的未来作用包括“液体活检”的进步，其中无需组织活检即可分析外周血样本中的肿瘤成分。
Lung cancer continues to be a major cause of death throughout the world. The ability to both accurately diagnose lung cancer in its early stages and monitor response to treatment is essential to reducing the morbidity and mortality associated with the disease. Serum tumor markers have been identified as potential biomarkers that may aid in lung cancer diagnosis and surveillance. These markers, when combined with cross-sectional imaging, may result in more robust screening and surveillance protocols. The future role of serum tumor markers in lung cancer includes the advancement of "liquid biopsies," in which peripheral blood samples are analyzed for tumor components without the need for a tissue biopsy.

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Vos D, Rao S, Pierce JD, Smith DA, Tirumani SH, Yoest JM, Ramaiya NH. The Past, Present, and Future (Liquid Biopsy) of Serum Tumor Markers in Lung Cancer: A Primer for the Radiologist. J Comput Assist Tomogr. 2021 Aug 2. doi: 10.1097/RCT.0000000000001204. Epub ahead of print. PMID: 34347703.

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